Gm-csf inhibiting oligopeptides

Details Gm-csf inhibiting oligopeptides Gm-csf inhibiting oligopeptides

C - Chemistry, Metallurgy

12

P

C12P 21/08 (2006.01) A61K 39/395 (2006.01) C07K 7/08 (2006.01) C07K 14/535 (2006.01) C07K 16/24 (2006.01) C12N 5/18 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2060741

ABSTRACT Provided are antibodies which are capable of inhibiting the biological activity of a granulocyte- macrophage colony stimulating factor ( "GM-CSF"). These antibodies are useful for alleviating undesirable biological effects mediated by GM-CSF. In particular, the antibodies are useful for inhibiting the growth of a GM-CSF dependent neoplastic disease. Also provided are formulations and methods for using the antibodies of the invention.

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