C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/11 (2006.01) A61K 31/713 (2006.01) A61K 38/17 (2006.01) A61P 3/04 (2006.01) A61P 3/06 (2006.01) A61P 3/10 (2006.01) A61P 9/10 (2006.01) A61P 9/12 (2006.01) C07K 14/435 (2006.01)
Patent
CA 2453653
The present invention relates to the field of obesity research. Obesity is a public health problem that is serious and widespread. A compound, homotrimer of GMG-2 polypeptide fragment comprising globular domain and all or part of GMG-2 collagen-like region, has been identified that has utility for reducing body mass, for maintaining weight loss, and for treating obesity-related diseases and disorders. These obesity-related diseases and disorders include hyperlipidemias, atherosclerosis, diabetes, and hypertension.
La présente invention a trait au domaine de la recherche contre l'obésité, problème de santé publique grave et répandu. Un composé, homotrimère d'un fragment du polypeptide GMG-2 comprenant un domaine globulaire et tout ou partie d'un domaine de type collagène GMG-2, qui permet de réduire la masse corporelle, de maintenir la perte de poids et de traiter les maladies et les troubles liés à l'obésité, a été identifié. Lesdits maladies et troubles liés à l'obésité comprennent les hyperlipidémies, l'athéroscléroses, le diabète et l'hypertension.
Dialynas Deno
Lucas John
Scalia Aaron
Tanaka Hiroaki
Genset S.a.
Kirby Eades Gale Baker
Serono Genetics Institute S.a.
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