C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2677799
The present invention provides methods of detecting mutations in a Gnaq gene in a melanocytic neoplasm for diagnostic and prognostic purposes. The invention further provides methods of treating such melanocytic neoplasm by modulating the activity of the mutated Gnaq gene.
La présente invention concerne des procédés consistant à détecter des mutations d'un gène Gnaq dans néoplasme mélanocytique à des fins de diagnostic et de pronostique. L'invention concerne en outre des procédés consistant à traiter un tel néoplasme mélanocytique en modulant l'activité du gène Gnaq muté.
Barsh Gregory S.
Bastian Boris C.
Van Raamsdonk Catherine D.
Smart & Biggar
The Board Of Trustees Of The Leland Stanford Junior University
The Regents Of The University Of California
The University Of British Columbia
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