Gonadal function improving agents

Details Gonadal function improving agents Gonadal function improving agents

A - Human Necessities

61

K

A61K 38/22 (2006.01) A61K 31/7088 (2006.01) A61K 38/08 (2006.01) A61K 38/17 (2006.01) A61K 45/00 (2006.01) A61P 5/08 (2006.01) A61P 15/08 (2006.01) A61P 35/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/15 (2006.01) G01N 33/50 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2518541

Metastin and compounds promoting the activity of metastin or its receptor are useful as excellent gonadal function improving agents, ovulation inducers or promoters, gonadotropin secretion promoters, gonadotropin secretion inhibitors, sexual hormone secretion promoters, sexual hormone secretion inhibitors and so on to be used in preventives and remedies for infertility, hormone-sensitive cancer, endometriosis, etc. Metastin and its receptor are useful in screening these drugs.

L'invention porte sur la métastine et des composés renforçant l'activité de la métastine ou de ses récepteurs, qui s'avèrent d'excellents: agents d'amélioration de la fonction gonadique, inducteurs et promoteurs de l'ovulation, promoteurs de la sécrétion de gonadotrophine, promoteurs de la sécrétion des hormones sexuelles, inhibiteurs de la sécrétion des hormones sexuelles, etc., pouvant servir à traiter la stérilité, les cancers hormono-réceptifs, les endométrioses, etc., la métastine et ses récepteurs pouvant par ailleurs servir pour le criblage de ces médicaments.

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