Gonadotropin releasing hormone antagonist

A - Human Necessities – 61 – K

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Details

A61K 38/09 (2006.01) A61P 5/04 (2006.01)

Patent

CA 2341974

The present invention relates to a method to prevent a premature LH surge. The method employs the administration of the gonadotropin releasing hormone antagonist ganirelix in an amount dependent on the body weight of the patient. The method can be used in combination with administration of exogenous FSH in the treatment of women undergoing controlled ovarian superovulation.

L'invention concerne un procédé servant à empêcher une montée prématurée de l'hormone de lutéinisation (LH). Ce procédé consiste à administrer l'antagoniste de l'hormone de libération des gonadotrophines ganirelix selon une quantité dépendante du poids corporel de la patiente. On peut combiner ce procédé à l'utilisation de l'hormone exogène de stimulation des follicules (FSH) afin de traiter des femmes en cours de superovulation contrôlée.

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