Gp286 nucleic acids and polypeptides

Details Gp286 nucleic acids and polypeptides Gp286 nucleic acids and polypeptides

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 31/7088 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12N 5/10 (2006.01) C12N 15/62 (2006.01) C12Q 1/68 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2412610

An isolated polynucleotide encoding a novel immunoglobulin superfamily member named GP286 is provided. GP286 has a predicted single membrane spanning domain and one immunoglobulin (Ig) domain in the extracellular portion of the protein. The protein structure and tissue distribution of GP286 indicate that it plays a role in cell-cell recognition, binding, signaling and adhesion events in the immune system. Provided by the invention are isolated GP286 related polynucleotides and polypeptides, vectors, and host cells comprisingany of the above, antibodies directed to GP286, cells which produce such antibodies, and related diagnostic and therapeutic methods.

La présente invention concerne un polynucléotide isolé codant un nouveau membre de la superfamille d'immunoglobuline, appelé GP286. GP286 présente un domaine de recouvrement de membrane unique prédéterminé et un domaine d'immunoglobuline (Ig) dans la partie extracellulaire de la protéine. La structure de la protéine et la répartition tissulaire de GP286 donnent une indication sur son rôle majeur dans les événements de reconnaissance entre cellules, de liaison, de signalisation, et d'adhérence dans le système immunitaire. Par ailleurs, cette invention concerne des polynucléotides et des polypeptides de GP286 isolés, des vecteurs et des cellules hôtes contenant l'un ou l'autre de ces éléments, des anticorps dirigés contre GP286, des cellules qui produisent ce type d'anticorps, ainsi que des méthodes diagnostiques et thérapeutiques associées.

Affiliated with

Also associated with

Rating

Gp286 nucleic acids and polypeptides does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Gp286 nucleic acids and polypeptides, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Gp286 nucleic acids and polypeptides will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1673323