Gpcr-like retinoic acid-induced gene 1 protein and nucleic acid

Details Gpcr-like retinoic acid-induced gene 1 protein and nucleic acid Gpcr-like retinoic acid-induced gene 1 protein and nucleic acid

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A01K 67/027 (2006.01) A61K 31/7088 (2006.01) A61K 45/00 (2006.01) A61K 48/00 (2006.01) C07K 14/575 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12N 15/63 (2006.01) C12Q 1/68 (2006.01) G01N 33/566 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2457496

A novel G-protein coupled receptor-like retinoic acid induced molecule was identified as being differentially expressed (GPCR-like RAIG1) in an animal model of fasting and feeding. Compositions and methods pertaining to treatment and diagnosis of various metabolic disorders, such as cachexia and obesity.

Selon l'invention, on a identifié une nouvelle molécule induite par l'acide rétinoïque de type GPCR (récepteur couplé aux protéines G) comme étant exprimée de façon différentielle (RAIG1 de type GPCR) dans un modèle animal de jeûne et d'alimentation. L'invention décrit des compositions et des méthodes qui concernent le traitement et le diagnostic de différents troubles du métabolisme, tels que la cachexie et l'obésité.

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