G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/53 (2006.01) G01N 33/566 (2006.01) G01N 33/574 (2006.01) G01N 33/68 (2006.01) G01N 33/74 (2006.01)
Patent
CA 2454135
Human GPC genes are identified as modulators of the IRRTK of p21 pathways, and thus are therapeutic targets for disorders associated with defective IRRTK or p21 function. Methods for identifying modulators of IRRTK or p21, comprising screening for agents that modulate the activity of GPC are provided.
On a identifié des gènes GPC humains en tant que modulateurs des mécanismes de IRRTK ou de p21, et par conséquent ces derniers sont devenus des cibles thérapeutiques pour des troubles associés à un dysfonctionnement de IRRTK ou de p21. Cette invention concerne également des méthodes d'identification de modulateurs de IRRTK ou de p21, comprenant le criblage d'agents qui modulent l'activité de GPC.
Friedman Lori
Funke Roel P.
Kidd Thomas
Li Danxi
Plowman Gregory D.
Bennett Jones Llp
Exelixis Inc.
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