Graft with increased resistance to enzymatic degradation

Details Graft with increased resistance to enzymatic degradation Graft with increased resistance to enzymatic degradation

A - Human Necessities

61

L

A61L 27/36 (2006.01)

Patent

CA 2575240

Described are devices, methods, and systems for grafting tissues or organs that are exposed to bacterial or mammalian enzymes that degrade collagenous materials. Illustrative medical grafts are processed by contacting a collagenous extracellular matrix (ECM) material with a mono-carboxylic acid having from four to about twelve carbon atoms, or mixtures of two or more such acids.

L'invention concerne des dispositifs, des méthodes et des systèmes de greffe de tissus ou d'organes qui sont exposés aux enzymes bactériennes ou mammifères lesquelles dégradent les matières collagènes. Des greffons médicaux pris à titre d'exemple sont traités par contact d'une matière de matrice extracellulaire collagène (ECM) avec un acide monocarboxylique comportant de quatre à environ douze atomes de carbone, ou des mélanges de deux de ces acides ou davantage.

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