Gram-positive bacteria deprived of htra proteasic activity...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/57 (2006.01) C12N 9/52 (2006.01) C12N 15/74 (2006.01)

Patent

CA 2356740

The invention concerns bacteria strains, obtained from gram-positive bacteria whereof the genome size is not more than 3.2 Mb, and wherein the HtrA surface protease is inactive. Said strains are useful for expressing exported proteins of interest.

L'invention concerne des souches bactériennes, obtenues à partir de bactéries à gram-positif dont la taille du génome est au plus égale à 3,2 Mb, et dans lesquelles la protéase de surface HtrA est inactive. Ces souches sont utilisables pour l'expression de protéines d'intérêt exportées.

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