Gram-positive expression control sequences

Details Gram-positive expression control sequences Gram-positive expression control sequences

C - Chemistry, Metallurgy

12

N

195/1.2, 195/1.2

C12N 15/75 (2006.01) C12N 1/21 (2006.01) C12N 15/70 (2006.01)

Patent

CA 1316850

4754/5 ABSTRACT ABSTRACT New gram-positive expression control DNA sequences useful in the expression of pro- or eukaryotic proteins in gram-positive organisms are provided having in the down- stream direction of transcription a transcription ini- tiation DNA sequence of gram-negative origin combined with a ribosome binding site-encoding DNA sequence, optionally a foreign gene and a transcription termination sequence. Also described are expression vectors containing these expres- sion control DNA sequences and processes using same for the manufacture of pro- and eukaryotic polypeptides. In addi- tion processes for the manufacture of such gram-positive expression control DNA sequences and such expression vectors are described.

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