A - Human Necessities – 23 – K
Patent
A - Human Necessities
23
K
99/30
A23K 1/16 (2006.01) A23K 1/00 (2006.01) A23K 1/18 (2006.01) A61K 9/16 (2006.01)
Patent
CA 1331713
- 20 - GRANULAR COMPOSITION FOR RUMINANT ABSTRACT OF THE DISCLOSURE A granular composition for a ruminant containing as a main component choline or a physiologically acceptable derivative thereof, wherein the composition is prepared by (1) granulating the choline or it derivative having an average particle size of 100 µm or less and a maximum particle size of 150 µm or less, an excipient having an average particle size of 10 µm or less and a maximum particle size of 20 µm or less, and a hydrophobic binder under a relative humidity of 10% or less by using an agitation granulator, followed by cooling, separating and classifying the resultant granules to obtain spherical granules having a particle size of 0.5 to 2.5 mm and (ii) forming a thin film on the surface of the granules at a temperature of at least 5°C less than a melting point of the binder and 5°C to 25°C less than a melting point of the overcoating agent under a relative humidity of 30% or less in an agitation granu- lator by adding 20 to 40 parts by weight, based on 100 parts by weight of the granules, of a heated molten mixture of a hydrophobic overcoating agent and a solu- bility modifier in the form of a fine powder in a weight ratio of 1:0.2-1.
587272
Iijima Hitoshi
Kiuchi Masayuki
Nakao Masahiro
Nishimura Kunio
Sato Shigeaki
Ridout & Maybee Llp
Showa Denko Kabushikikaisha
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