Granular material comprising water-insoluble inorganic...

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A61K 9/16 (2006.01) A61K 9/20 (2006.01) A61K 9/28 (2006.01) A61K 33/06 (2006.01) A61K 33/24 (2006.01) A61K 33/26 (2006.01) A61K 45/06 (2006.01) A61P 7/00 (2006.01) C01F 7/00 (2006.01) C01G 49/00 (2006.01)

Patent

CA 2633762

There is provided a granular material comprising (i) at least 50 % by weight based on the weight of the granular material of solid water-insoluble mixed metal compound capable of binding phosphate of formula (I): M II1-x MIII x(OH)2A n- y.ZH2O (I) where M II is at least one of magnesium, calcium, lanthanum and cerium; M III is at least iron(III); A is at least one n-valent anion; x = .SIGMA.ny; 0 < x<= 0.67, 0 < y <= 1, and 0 <= z < 10; (ii) from 3 to 12 % by weight based on the weight of the granular material of non-chemically bound water, and (iii) no greater than 47 % by weight based on the weight of the granular material of excipient.

La présente invention concerne un matériau granulaire comprenant (i) au moins 50 % en poids sur la base du poids du matériau granulaire d'un composé métallique mixte solide insoluble dans l'eau capable de se lier à un phosphate répondant à la formule (I): M<SUP>II</SUP> <SUB>1-X</sub

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