Granulate comprising escitalopram oxalate

Details Granulate comprising escitalopram oxalate Granulate comprising escitalopram oxalate

A - Human Necessities

61

K

A61K 9/16 (2006.01) A61K 9/28 (2006.01) A61K 31/343 (2006.01)

Patent

CA 2722802

The invention relates to a granulate comprising escitalopram oxalate having an average particle size of less than 100 µm and at least one filler. The invention further relates to a method of producing that granulate and also to a tablet or capsule comprising that granulate and/or obtained by compressing that granulate to form a tablet or by filling that granulate into a capsule shell. Finally, the invention relates to the use of that granulate and/or tablet or capsule in the treatment or prevention of a disorder from the spectrum of depressive disorders.

L'invention porte sur des granulés contenant de l'oxalate d'escitalopram présentant une dimension moyenne de particule inférieure à 100 µm et au moins une charge. L'invention porte en outre sur un procédé de fabrication de ces granulés ainsi que sur des comprimés ou capsules contenant ces granulés et/ou obtenus par compression de ces granulés pour former un comprimé ou par remplissage de coques de capsules par ces granulés. Enfin, l'invention porte sur l'utilisation de ces granulés et/ou de ces comprimés ou capsules dans le traitement ou la prévention d'un trouble appartenant au spectre des troubles dépressifs.

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