Granulated particles with masked taste

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/16 (2006.01) A61K 9/00 (2006.01) A61K 9/50 (2006.01)

Patent

CA 2403757

Pellets of granulated particles comprising at least one pharmaceutically active compound, which pellets are characterised in that a bad taste of a pharmaceutically active compound when taken by patients is reduced or eliminated, said pellets comprise a pharmaceutically active compound and further comprise an organic carboxylic acid and/or a surfactant and/or a hydrocolloid and said pellets are coated with an enteric film-forming composition comprising an enteric film-forming component and pharmaceutical compositions comprising such pellets.

L'invention concerne des comprimés de particules granulées comprenant au moins un composé pharmaceutiquement actif. Ces comprimés sont caractérisés par le fait que le mauvais goût d'un composé pharmaceutiquement actif lorsqu'il est avalé par un patient est réduit ou éliminé. Ces comprimés renferment un composé pharmaceutiquement actif et également un acide carboxylique et/ou un surfactant et/ou un hydrocolloïde organique et ces comprimés sont revêtus d'une composition formant un film kératinisé renfermant un composé formant un film kératinisé. L'invention concerne également une composition pharmaceutique comprenant ces comprimés.

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