Granules having core and their production

Details Granules having core and their production Granules having core and their production

A - Human Necessities

61

K

167/169

A61K 9/16 (2006.01) A61K 9/20 (2006.01) A61K 9/50 (2006.01)

Patent

CA 1338596

Granules having a core are produced by spraying core granules with a dispersion of a low substituted hydroxypropylcellulose (L-HPC), and if necessary, simultaneously applying a dusting powder. The granules having a core thus obtained exhibit increased granule strength and improved disintegrating property as compared with those produced by known methods. An active ingredient such as a drug can be contained in the dispersion, dusting powder or core granules.

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