Granules of thiamine salt and the production thereof

Details Granules of thiamine salt and the production thereof Granules of thiamine salt and the production thereof

A - Human Necessities

61

K

167/150

A61K 9/16 (2006.01) A61K 9/20 (2006.01) A61K 9/50 (2006.01) A61K 31/51 (2006.01)

Patent

CA 1279014

Abstract of the Disclosure Granules consisting of a thiamine salt and a binder such as water-soluble celluloses, said thiamine salt accounting for about 95 to about 98 percent by weight on the dried basis can be prepared by spray-coat- ing thiamine salt powder at least about 95 percent by weight of which is capable of passing through a 145-mesh sieve with a solution containing a binder while maintain- ing said thiamine salt powder in a fluidized state in a fluidized-bed granulation apparatus. The granules are excellent in flowability, mix- ability, compressibility and bonding properties, and can be used for tablet manufacturing.

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