Granulocyte-macrophage colony-stimulating factor (gm-csf)...

Details Granulocyte-macrophage colony-stimulating factor (gm-csf)... Granulocyte-macrophage colony-stimulating factor (gm-csf)...

C - Chemistry, Metallurgy

07

K

C07K 16/24 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01) A61P 37/02 (2006.01)

Patent

CA 2759506

The invention provides a GM-CSF neutralizing human monoclonal antibody, 1783J22, as well as methods of mak-ing and use thereof. The monoclonal antibody is further characterized by its ability to bind epitopes from GM-CSF proteins of multiple species.

L'invention concerne un anticorps monoclonal humain 1783J22 neutralisant le GM-CSF, ainsi que des procédés pour le préparer et l'utiliser. L'anticorps monoclonal est en outre caractérisé par sa capacité à se lier aux épitopes de protéines GM-CSF de multiples espèces.

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