Granulocyte subtype-selective receptors and ion channels and...

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/68 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2600108

The invention relates, in part, to granulocyte type selective markers that are preferentially expressed in granulocytes and their use in drug screening assays. Additionally, the granulocyte type selective markers are useful in the diagnosis and treatment of granulocyte disorders and in the assessment of the efficacy of therapies of granulocyte disorders.

L'invention concerne partiellement des marqueurs sélectifs de type granulocyte, de préférence exprimés dans des granulocytes, et leur utilisation dans des essais de criblage de médicament. En outre, ces marqueurs sélectifs de type granulocyte sont utilisés dans le diagnostic et dans le traitement de troubles granulocytaires et dans l'évaluation de l'efficacité de thérapies de troubles granulocytaires.

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