Grape extract, dietary supplement thereof, and processes...

A - Human Necessities – 61 – K

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A61K 36/87 (2006.01) A23L 2/00 (2006.01)

Patent

CA 2623414

The present invention relates to a novel grape extract, and processes for making such, that is useful for, inter alia, treating pre-hypertension, Metabolic Syndrome and/or the conditions that comprise Metabolic Syndrome. The processes of the present invention produce a highly concentrated polyphenol product by maximizing extraction of monomeric and oligomeric procyanidins and minimizing extraction of polymeric procyanidins. The grape extract of the present invention comprises between about 5-15% monomers, about 5-20% dinners, about 3- 10% trimers, about 2-10% tetramers, and about 2-10% pentamers by weight. The grape extract of the present invention can be formulated into dietary supplements, including capsules, tablets, powders, solutions, gels, suspensions, creams, gels, and the like. These dietary supplements in, for instance, powder or solution form, may be added to nutraceuticals, foods and/or beverages to form functional nutraceutical, food, and/or beverage products.

La présente invention concerne un nouvel extrait de raisin, et des procédés pour les préparer, l'extrait de raisin étant utile, entre autres, pour traiter la pré-hypertension, le syndrome métabolique et/ou des états pathologiques qui comprennent le syndrome métabolique. Les procédés de l'invention permettent l'obtention d'un produit de polyphénol fortement concentré en maximisant l'extraction de procyanidines monomères et oligomères, et en minimisant l'extraction de procyanidines polymères. L'extrait de raisin de l'invention comprend en poids environ 5-15 % de monomères, environ 5-20 % de dimères, environ 3- 10 % de trimères, environ 2-10 % de tétramères, et environ 2-10 % de pentamères. L'extrait de raisin de l'invention peut être formulé dans des compléments alimentaires comprenant des capsules, des comprimés, des poudres, des solutions, des gels, des suspensions, des crèmes, et analogues. Ces compléments alimentaires, par exemple sous forme de poudre ou de solution, peuvent être ajoutés à des nutraceutiques, des aliments et/ou des boissons pour former des produits nutraceutiques, des produits alimentaires et/ou des produits à boire.

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