Grb7 family proteins and the insulin receptor for screening...

Details Grb7 family proteins and the insulin receptor for screening... Grb7 family proteins and the insulin receptor for screening...

G - Physics

01

N

G01N 33/74 (2006.01) G01N 33/566 (2006.01) G01N 33/573 (2006.01)

Patent

CA 2366277

The invention concerns the use of Grb14 and homologous adapting proteins, as tool for screening molecules designed for the treatment of diseases involving insulin. The invention also concerns a method for detecting molecules capable of modulating the tyrosine kinase activity of the insulin receptor.

L'invention se rapporte à l'utilisation de la protéine Grb14 et des protéines adaptatrices homologues, comme outil de criblage de molécules destinées au traitement des maladies impliquant l'insuline. L'invention se rapporte également à un procédé de détection des molécules aptes à moduler l'activité tyrosine kinase du récepteur de l'insuline.

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