C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
167/103, 530/7.1
C07K 7/10 (1985.01) A61K 37/02 (1985.01) A61K 37/24 (1985.01)
Patent
CA 1271899
GRF ANALOGS ABSTRACT OF THE DISCLOSURE Synthetic peptides are extremely potent in stimulating the release of pituitary GH in mammals because they are the replicates of the native (hormone) releasing factor of the hypothalamus of the particular species, i.e. porcine, bovine and caprine. These peptides contain the following sequence: Image wherein R28 is Ser or Asn; and R41 is Arg or Lys. The peptide or a biologically active fragment thereof, or analogs thereof having well-known substitutions and/or additions, as well as nontoxic salts of any of the foregoing, may be administered to mammals and may be used diagnostically. The peptides are particularly useful in stimulating the release of GH so as to accelerate growth in warm-blooded non-human animals of the particular species and/or to improve aquiculture.
461900
Bohlen Peter
Brazeau Paul Ernest
Esch Frederick Stephen
Guillemin Roger Charles Louis
Ling Nicholas Chai-Kwan
Macrae & Co.
The Salk Institute For Biological Studies
LandOfFree
Grf analogs does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Grf analogs, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Grf analogs will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1182195