Griseolic acid derivatives, and their use

Details Griseolic acid derivatives, and their use Griseolic acid derivatives, and their use

C - Chemistry, Metallurgy

07

H

260/210, 260/242

C07H 19/16 (2006.01) C07H 19/02 (2006.01) C07H 23/00 (2006.01)

Patent

CA 1267408

ABSTRACT OF THE DISCLOSURE Griseolic acid derivatives of formula (I): (I) Image wherein A represents: Image or Image ; have enzyme inhibitory activity, especially against cAMP PDE and cGMP PDE. When formulated as compositions with appropraite carriers or diluents, they may be used for the treatment of a variety of organic disorders and show toxicities less than griseolic acid itself.

466527

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