Growth arrest gene compositions and methods

Details Growth arrest gene compositions and methods Growth arrest gene compositions and methods

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) C07K 14/705 (2006.01) C07K 14/71 (2006.01) G01N 33/554 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2259337

Disclosed is a novel gene and growth arrest gene product encoded by the gene. Expression of the growth arrest gene B4B results in inhibition of cellular proliferation. The gene and gene product serve as markers of cancerous or pre- cancerous conditions, and as markers of immune states.

La présente invention concerne un gène et un produit génique d'arrêt de croissance codé par ce gène. L'expression du gène d'arrêt de croissance B4B provoque le blocage de la prolifération cellulaire. Ce gène ainsi que le produit génique de l'invention conviennent comme marqueurs spécifiques des états cancéreux ou précancéreux, et comme marqueurs des états immunitaires.

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