Growth factor delivery system for the healing of wounds and...

A - Human Necessities – 61 – K

Patent

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A61K 9/00 (2006.01) A61K 9/58 (2006.01) A61K 38/18 (2006.01) A61K 38/27 (2006.01) A61K 47/32 (2006.01)

Patent

CA 2483265

The present invention features hydrogel drug delivery systems and methods of producing and using such systems for the treatment of wounds. The systems are based on a hydrogel into which a low concentration of growth factor, e.g., epidermal growth factor, is passively transferred from a dilute aqueous solution. When placed in contact with a wounded tissue, the growth factor passively transfers out of the contact lens to provide accelerated healing. The systems are applicable to ocular and other wound treatments.

La présente invention concerne des systèmes d'administration de médicaments sous forme d'hydrogel, ainsi que des méthodes de production et d'utilisation de tels systèmes pour le traitement de plaies. Ces systèmes sont constitués d'un hydrogel dans lequel une faible concentration d'un facteur de croissance, tel que le facteur de croissance épidermique, par exemple, est transféré passivement à partir d'une solution aqueuse diluée. Lorsqu'il est mis en contact avec un tissu blessé, le facteur de croissance est transféré de manière passive à partir de la lentille pour accélérer le traitement de la plaie. Ces systèmes sont conçus pour le traitements des lésions oculaires et pour le traitement d'autres types de plaies.

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