Growth hormone antagonists

Details Growth hormone antagonists Growth hormone antagonists

C - Chemistry, Metallurgy

12

N

C12N 15/18 (2006.01) A01K 67/027 (2006.01) A61K 38/27 (2006.01) C07K 14/61 (2006.01) C12N 5/10 (2006.01) C12N 15/85 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2102129

The present invention relates to growth inhibitory antagonists of bovine growth hormone obtained by mutation of the third alpha helix of that protein. These novel hormones may be administered exogenously to animals, or transgenic animals may be made that express the antagonist and thereby exhibited a reduced growth phenotype.

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