Growth hormone antagonists

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/18 (2006.01) A01K 67/027 (2006.01) A61K 38/27 (2006.01) A61K 48/00 (2006.01) C07K 14/61 (2006.01) C12N 15/85 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2067136

The present invention relates to growth inhibitory antagonists of bo- vine growth hormone obtained by mu- tation of the third alpha helix of that protein. These novel hormones may be administered exogenously to animals, or transgenic animals may be made that express the antagonist and thereby exhibited a reduced growth phenotype.

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