Growth hormone crystals and a process for production of...

Details Growth hormone crystals and a process for production of... Growth hormone crystals and a process for production of...

C - Chemistry, Metallurgy

07

K

C07K 14/61 (2006.01) A61K 38/27 (2006.01) C07K 1/30 (2006.01) C30B 7/00 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2086087

A process for production of canon crystals of GH (Growth Hormone) or of GH derivatives. The process comprises the following steps: (a) to a solution of GH or a derivative thereof is added cations of inorganic or organic nature and at least one organic solvent at a pH in the range of from about 5.0 to about 6.8; (b) growing of crystals at a temperature in the range of from about 0° to about 30°C; and (c) isolation of the cation crystals. An aspect of the invention also relates to cation crystals of hGH (human Growth Hormone) or hGH derivatives.

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