C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/18 (2006.01) A61K 31/7088 (2006.01) A61K 38/27 (2006.01) A61K 48/00 (2006.01) A61P 5/00 (2006.01) C07H 21/00 (2006.01) C07K 14/61 (2006.01) C07K 16/26 (2006.01) C12P 21/02 (2006.01) C12Q 1/48 (2006.01) C12Q 1/68 (2006.01) G01N 33/68 (2006.01) G01N 33/74 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2503672
The present invention relates to a naturally-occurring growth hormone mutation; to a method for detecting it and its use in screening patients for growth hormone dysfunction or for producing variant proteins suitable for treating such irregularities.
La présente invention concerne une mutation naturelle de l'hormone de croissance, un procédé de détection de cette mutation, et son utilisation dans le criblage de patients visant à déterminer des dysfonctionnements de l'hormone de croissance, et dans la production de variants de protéines adaptés au traitement de tels troubles.
Cooper David Neil
Gregory John
Lewis Mark
Millar David Stuart
Procter Anne Marie
Smart & Biggar
University College Cardiff Consultants Limited
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