C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 1/20 (2006.01) C12N 9/52 (2006.01)
Patent
CA 2668353
The present invention provides improved media for the cultivation of Clostridium histolyticum and culture supernatants for the biotechnological production of collagenase enzymes. The nutrient media according to the invention comprise one or more peptones from a non-mammalian source, preferablyplant-derived peptones. The media can additionally comprise fish gelatin. The invention provides media, culture supernatants comprising Clostridium histolyticum collagenase, and methods to produce said collagenase.
Hoffmann Artur
Marx Thomas
Sonn Kirsten
Suppmann Bernhard
Thalhofer Johann-Peter
Borden Ladner Gervais Llp
F. Hoffmann-La Roche Ag
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