Grp94-based compositions and methods of use thereof

C - Chemistry – Metallurgy – 07 – H

Patent

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Details

C07H 21/04 (2006.01) A61K 48/00 (2006.01) C07K 17/00 (2006.01) C12N 5/00 (2006.01) C12N 15/00 (2006.01) C12N 15/74 (2006.01)

Patent

CA 2525385

Mini chaperones and methods of use thereof for the treatment of cancer and other disorders are provided. Also provided are tools to facilitate screening therapeutic agents which have selective binding affinity for GRP94.

L'invention concerne des mini chaperons moléculaires et des procédés d'utilisation associés dans le traitement du cancer et d'autres troubles. L'invention concerne également des outils pour faciliter le criblage d'agents thérapeutiques qui ont une affinité de liaison sélective avec GRP94.

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