Gtpase activating proteins

Details Gtpase activating proteins Gtpase activating proteins

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A01K 67/027 (2006.01) A61K 38/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 15/11 (2006.01) C12Q 1/68 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2398825

The invention provides mammalian nucleic acid molecules and fragments thereof. It also provides for the use of the mammalian nucleic acid molecules for the characterization, diagnosis, evaluation, treatment, or prevention of conditions, diseases and disorders associated with cell signaling, the immune system, and cell proliferation, particularly colon cancer. The invention additionally provides expression vectors and host cells for the production of the protein encoded by the mammalian nucleic acid molecules.

L'invention concerne des molécules d'acide nucléique mammaliennes et des fragments de celles-ci. L'invention concerne également l'utilisation des molécules d'acide nucléique mammaliennes dans la caractérisation, le diagnostic, l'évaluation, le traitement, ou la prévention des états pathologiques, des maladies et des troubles associés à la signalisation cellulaire, au système immunitaire, et à la prolifération cellulaire, en particulier le cancer du côlon. L'invention concerne en outre des vecteurs d'expression et des cellules hôtes intervenant dans la production de la protéine codée par les molécules d'acide nucléique mammaliennes.

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