Guanidine derivatives

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 313/08 (2006.01) A61K 31/155 (2006.01) A61K 31/335 (2006.01) A61K 31/4025 (2006.01) A61K 31/5377 (2006.01) A61K 31/55 (2006.01) A61P 9/00 (2006.01) A61P 9/02 (2006.01) A61P 9/10 (2006.01) A61P 13/12 (2006.01) C07C 279/22 (2006.01) C07D 223/16 (2006.01) C07D 233/16 (2006.01) C07D 279/22 (2006.01) C07D 337/08 (2006.01) C07D 405/04 (2006.01) C07D 409/04 (2006.01)

Patent

CA 2325736

This invention relates to guanidine derivatives of formula (I) wherein each symbol is as defined in the description, and its pharmaceutically acceptable salt, to processes for preparation thereof, to pharmaceutical composition comprising the same, and to a use of the same for treating cardiovascular diseases, cerebrovascular diseases, renal diseases, arteriosclerosis, shock and the like in human being and animals.

L'invention concerne des dérivés de guanidine représentés par la formule (I), dans laquelle chaque symbole possède la signification établie dans le descriptif, ainsi que leur sel acceptable sur le plan pharmaceutique, des procédés servant à les préparer, une composition pharmaceutique les contenant et leur utilisation afin de traiter des maladies cardiovasculaires, des maladies cérébrovasculaires, des maladies rénales, l'artériosclérose, les états de choc et des maladies semblables chez l'homme et chez l'animal.

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