Guanidine derivatives

Details Guanidine derivatives Guanidine derivatives

C - Chemistry, Metallurgy

07

C

C07C 279/22 (2006.01) A61K 31/16 (2006.01) A61K 31/40 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) C07D 295/13 (2006.01) C07D 295/15 (2006.01)

Patent

CA 2241915

Guanidine derivatives of formula (I) wherein R1 is [di(lower)alkylamino](lower)alkyl, morpholinyl(lower)alkyl, lower alkylpiperazinyl or [lower alkylpyrrolidinyl](lower)alkyl, R2 is halogen , lower alkyl or lower alkoxy, and R3 is halogen, lower alkyl, lower alkoxy or mono(or di or tri)halo(lower)alkyl, and pharmaceutically acceptable salts thereof which are useful as a medicament.

L'invention concerne les dérivés de la guanidine correspondant à la formule (I) dans laquelle R?1¿ représente [dialkylamino(inférieur)]alkyle(inférieur), morpholinylalkyle(inférieur), alkylpipérazinyle inférieur ou [alkylpyrrolidinyle inférieur]alkyle(inférieur), R?2¿ représente halogène, alkyle inférieur ou alcoxy inférieur et R?3¿ représente halogène, alkyle inférieur, alcoxy inférieur ou mono(ou di ou tri)haloalkyle(inférieur), et leur sels pharmaceutiquement acceptables. Les dérivés en question sont utiles comme médicament.

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