Guanidine derivatives

Details Guanidine derivatives Guanidine derivatives

C - Chemistry, Metallurgy

07

D

260/295, 260/474

C07D 213/75 (2006.01) C07C 129/12 (1980.01)

Patent

CA 1087180

ABSTRACT OF THE DISCLOSURE Guanidine derivatives of the formula:- Image in which R1 is a cyclohexyl, adamantyl, bicycloheptanyl, bicycloheptenyl, tricycloheptanyl or tetracyclononanyl radical and R2 ia a phenyl or pyridyl radical optionally substituted by 1 or 2 halogen atoms, or alkyl, cyanoalkyl, alkoxycarbonyl or amino radicals, and the pharmaceutically-acceptable acid- addition salts thereof, active against rhinoviruses, are disclosed, along with processes for their manuracture, compositions containing them, a method of combatting rhino- viral infections and a method of selectively killing rhino- viruses in a mixed virus population.

256739

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