Guanidine derivatives and therapeutic uses thereof

C - Chemistry – Metallurgy – 07 – D

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C07D 295/20 (2006.01) A61K 31/155 (2006.01) A61K 31/445 (2006.01) A61P 3/10 (2006.01) C07C 279/18 (2006.01) C07D 211/14 (2006.01) C07D 211/22 (2006.01)

Patent

CA 2574947

Compounds of the formula (I) in which the radicals R and R1 to R10 are as defined in the description, processes for the preparation of them, use thereof for the treatment of cardiovascular diseases, and pharmaceutical compositions comprising them.

Cette invention porte sur les composés représentés par la formule (I) dans laquelle les radicaux R et R1 à R10 sont tels que définis dans la description, sur des procédés de préparation de ces composés, sur leur utilisation dans le traitement de maladies cardiovasculaires ainsi que sur des compositions pharmaceutiques renfermant ces composés.

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