Guanidines

Details Guanidines Guanidines

C - Chemistry, Metallurgy

07

D

C07D 211/34 (2006.01) A61K 31/435 (2006.01) A61K 31/535 (2006.01) A61K 31/55 (2006.01) C07D 211/22 (2006.01) C07D 211/26 (2006.01) C07D 211/60 (2006.01) C07D 265/30 (2006.01) C07D 265/32 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 409/12 (2006.01) C07D 409/14 (2006.01) C07D 413/12 (2006.01)

Patent

CA 2044636

RAN 4044/69 Abstract The novel guanidines of the formula Image I wherein L, M, R, T and X have the significance given in the description, as well as hydrates or solvates thereof inhibit thrombin-induced platelet aggregation and clotting of fibrinogen in plasma. They are manufactured by amidination or, depending on whether L is NH or O, by amide formation or esterification.

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