Guanidinobenzoic ester derivative

C - Chemistry – Metallurgy – 07 – C

Patent

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C07C 323/63 (2006.01) C07C 323/20 (2006.01) C07D 207/404 (2006.01) C07D 207/408 (2006.01) C07D 209/48 (2006.01) C07D 263/44 (2006.01)

Patent

CA 1277669

Abstract of the Disclosure A guanidinobenzoic ester derivative having the formula is novel and effective to inhibit enzymes such as trypsin, plasmin and thrombin, being useful for treatment of the pancreatitis and hemorrhagic disease and thromhosis. Image wherein X represents a group of the formula: Image in which Y is a group of the formula: -(CH2)m-, m being an integer of 2 or 3, Image Image or Image or a group of the formula: -OR in which R is a hydrogen atom or a lower alkyl group, and n represents an lnteger of 1 to 5.

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