Guanidinyl heterocycle compounds useful as alpha-2...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 235/06 (2006.01) A61K 31/395 (2006.01) C07D 215/38 (2006.01) C07D 277/62 (2006.01)

Patent

CA 2272640

This invention involves compounds having structure (I) as described in the Claims; and enantiomers, optical isomers, stereoisomers, diastereomers, tautomers, addition salts, biohydrolyzables amides and esters thereof, as well as pharmaceutical compositions comprising such novel compounds. The invention also relates to the use of such compounds for preventing or treating disorders modulated by alpha-2 adrenoceptors.

La présente invention concerne des composés représentés par la formule générale (I) conformément à la description qu'en donnent les revendications. L'invention concerne également, non seulement des énantiomères, des isomères optiques, des stéréoisomères, des diastéréomères, des tautomères, des sels d'addition, des esters et des amides biohydrolysables de ces composés, mais aussi des compositions pharmaceutiques comprenant de tels composés. L'invention concerne enfin l'utilisation de ces composés pour la prévention ou le traitement de troubles imputables à la modulation par les adrénorécepteurs alpha-2.

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