Guinea pig model for leiomyomas and atherosclerosis

Details Guinea pig model for leiomyomas and atherosclerosis Guinea pig model for leiomyomas and atherosclerosis

C - Chemistry, Metallurgy

12

Q

C12Q 1/00 (2006.01) A01K 67/027 (2006.01) A61K 31/70 (2006.01) A61K 39/395 (2006.01) A61K 45/00 (2006.01) A61K 49/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/566 (2006.01) G01N 33/74 (2006.01)

Patent

CA 2235036

A method of making a model test system in guinea pigs for leiomyomas and early stage atherosclerosis by ovariectomizing young female guinea pigs, and co- implanting continuous slow release device for releasing an estrogenic compound or analogues thereof and a retinoid compound or analogues thereof.

Procédé d'élaboration d'un système d'expérimentation type sur des cobayes du léiomyome et de l'athérosclérose au premier stade par ovariectomie d'une jeune femelle cobaye et par implantation conjuguée d'un dispositif à libération lente et continue d'un composé d'oestrogènes ou d'analogues de ces substances et d'un composé rétinoïde ou d'analogues d'une telle substance.

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