Gustducin materials and methods

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A23L 1/22 (2006.01) A61K 39/395 (2006.01) C07K 7/08 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C07K 16/18 (2006.01) C07K 16/28 (2006.01) C12Q 1/44 (2006.01) G01N 33/566 (2006.01)

Patent

CA 2117795

A novel taste cell specific guanine nucleotide binding protein, gustducin, is disclosed as well as polynucleotide sequences encoding the a subunit of gustducin. Also disclosed are methods of modifying taste involving agents that inhibit or activate the gustducin a subunit, methods for identifying such taste modifying agents and various taste modifying agents.

L'invention décrit une nouvelle protéine de fixation de nucléotide de guanine spécifique à des cellules gustatives, dénommée gustducine, ainsi que les séquences de polynucléotide codant le sous-ensemble alpha de la gustducine. L'invention décrit également des procédés servant à modifier des agents gustatifs inhibant ou activant le sous-ensemble alpha de la gustducine, des procédés servant à identifier lesdits agents de modification gustative, ainsi que différents agents de modification gustative.

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