Gynecologic embolotherapy methods

Details Gynecologic embolotherapy methods Gynecologic embolotherapy methods

A - Human Necessities

61

M

A61M 1/20 (2006.01) A61B 17/42 (2006.01) A61B 17/00 (2006.01) A61B 17/12 (2006.01)

Patent

CA 2319193

This invention is directed to novel methods for gynecologic embolotherapy. The methods directly access the blood vessels to be embolized transcervically rather than arterially. The methods provide precise directed delivery of embolizing compositions, and are particularly suited for treating uterine fibroids. Kits containing one or more devices for transcervical injection and an embolizing composition are also provided. In a preferred embodiment, fluid embolizing compositions are used. In a more preferred embodiment, these fluid embolic compositions comprise a biocompatible polymer, a biocompatible solvent and a biocompatible water insoluble contrast agent. In a most preferred embodiment, the contrast agent is characterized by having an average particle size of about 10 µm or less.

L'invention concerne des procédés d'embolothérapie gynécologique, qui permettent d'accéder directement aux vaisseaux sanguins pour les besoins d'une embolisation transutérine plutôt qu'artérielle. Les procédés considérés permettent une administration directe précise de compositions d'embolisation, et ils se prêtent particulièrement bien au traitement des fibromes utérins. L'invention concerne également des kits renfermant un ou plusieurs dispositifs d'injection transutérine et une composition d'embolisation. En mode de réalisation préféré, on utilise des compositions d'embolisation liquides. Selon une variante préférée du même mode, lesdites compositions liquides renferment un polymère biocompatible, un solvant biocompatible et un agent de contraste biocompatible non hydrosoluble. Selon la variante préférée, l'agent de contraste est caractérisé en ce qu'il présente une taille de particule moyenne d'environ 10 µm ou moins.

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