A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/50 (2006.01) A61K 9/14 (2006.01) A61K 47/36 (2006.01)
Patent
CA 2602281
The present invention relates to a kind of sodium alginate microsphere vascular embolus containing gynecological drug and its preparation. The preparation of it consists of the following steps: preparing the solution of gynecological drug, sodium alginate and dilvalent metal cations such as BaCl2 , Mg Cl2 or CaCl2 etc. by order; mixing the gynecological drug solution and sodium alginate solution, and then mixing them with the curing solution of BaCl2 or CaCl2 and the like. Then the obtained is the sodium alginate microshere vascular embolus containing gynecological drug. The carrier materials of the vascular embolus according to the invention are natural extracts and have good biocompatibility and re biodegradable; the side effect of the pharmaceutic loaded by them is minimal, and it is especially suitable for myometrial gland and hysteromyoma.
L~invention concerne un suppositoire vasculaire microsphérique contenant des composés pharmaceutiques gynécologiques d~alginate de sodium et sa méthode de préparation. La méthode consiste en les préparations d~une solution de composés pharmaceutiques gynécologiques, d~une solution d'alginate de sodium et d~une solution de BaCl2 ou MgCl2. La solution de composés pharmaceutiques gynécologiques est mélangée à la solution d'alginate de sodium, et ensuite, le mélange obtenu est mélangé à la solution de BaCl2 ou MgCl2, appelée solution de solidification, afin d~obtenir le suppositoire vasculaire microsphérique d'alginate de sodium qui contient les composés pharmaceutiques gynécologiques. Les matériaux du porteur d'embolie vasculaire de l'invention sont des extraits naturels ; ils ont une bonne biocompatibilité, et minimisent les effets secondaires ; ils sont donc particulièrement indiqués pour le traitement de maladies gynécologiques tel que l'hystéromyome et les troubles des muscles des glandes utérines.
Hong Hong
Li Xinjian
Lu Ge
Xu Congjian
Beijing Shengyiyao Science & Technology Development Co. Ltd
Kirby Eades Gale Baker
Obstetrics And Gynecology Hospital Of Fudan University
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