C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/11 (2006.01)
Patent
CA 2675964
The invention relates to the treatment of rheumatoid arthritis, particularly to the use of nucleic acid agents capable of silencing H19 for the treatment of rheumatoid arthritis. The invention provides methods for ameliorating rheumatoid arthritis and symptoms associated therewith, utilizing gene silencing oligonucleotides such as small interfering RNA (siRNA) agents directed to H19.
L'invention porte sur le traitement de l'arthrite rhumatoïde, en particulier sur l'utilisation d'agents nucléotidiques capables d'inhiber H19 dans le but de traiter l'arthrite rhumatoïde. L'invention concerne des procédés qui permettent d'améliorer l'arthrite rhumatoïde et les symptômes associés, au moyen d'oligonucléotides de silençage génique tels que des agents à petits ARN interférants (ARNsi) dirigés contre H19.
Ridout & Maybee Llp
Yissum Research Development Company Of The Hebrew University Of
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