C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 17/10 (2006.01) A61K 38/42 (2006.01) A61K 47/48 (2006.01) C07K 14/805 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2258947
The present invention relates to novel oxygen carriers which contain haemoglobin-hydroxyethyl starch conjugates, and a process for the preparation thereof. The invention also relates to the use of said oxygen carriers as blood substitutes, plasma expanders, perfusion agents, haemodilution agents and/or cardioplegic solution. The object of the invention are oxygen carriers which contain a haemoglobin-hydroxyethyl starch conjugate in which the haemoglobin and the hydroxyethyl starch are linked selectively to each other via amide bonds between free amino groups of the haemoglobin and of the oxidised, reducing end group of the hydroxyethyl starch.
L'invention concerne de nouveaux agents de transport d'oxygène renfermant des conjugués hémoglobine-amidon hydroxyéthylé, ainsi que leur procédé de fabrication. L'invention concerne en outre l'utilisation des agents de transport d'oxygène comme succédanés du sang, succédanés du plasma sanguin, agents de perfusion, agents d'hémodilution et/ou solution cardioplégique. L'invention a plus particulièrement pour objet des agents de transport d'oxygène renfermant un conjugué hémoglobine-amidon hydroxyéthylé, dans lequel l'hémoglobine et l'amidon hydroxyéthylé sont liés sélectivement entre eux par l'intermédiaire de liaisons amides entre des groupes amino libres de l'hémoglobine et des groupes terminaux réduits, se présentant sous forme oxydée, de l'amidon hydroxyéthylé.
Eichner Wolfram
Sommermeyer Klaus
Fresenius Ag
Ridout & Maybee Llp
LandOfFree
Haemoglobin-hydroxyethyl starch conjugates as oxygen carriers does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Haemoglobin-hydroxyethyl starch conjugates as oxygen carriers, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Haemoglobin-hydroxyethyl starch conjugates as oxygen carriers will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1474320