Haemophilus adhesin protein

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/31 (2006.01) A61K 39/102 (2006.01) A61K 39/106 (2006.01) A61K 39/108 (2006.01) C07K 7/04 (2006.01) C07K 14/205 (2006.01) C07K 14/245 (2006.01) C07K 14/285 (2006.01) C07K 16/12 (2006.01)

Patent

CA 2182046

An adhesin protein which binds specifically to phosphatidylethanolamine (PE), gangliotriaosylceramide (Gg3) and gangliotetraosylceramide (Gg4) has been isolated and purified from H. influenzae. Also provided are immunogenic compositions and methods of protecting susceptible mammals from diseases caused by bacterial pathogens having the adhesin as a surface protein.

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