Haemophilus influenzae b polysaccharide exotoxoid conjugate...

Details Haemophilus influenzae b polysaccharide exotoxoid conjugate... Haemophilus influenzae b polysaccharide exotoxoid conjugate...

A - Human Necessities

61

K

167/129

A61K 39/295 (2006.01) A61K 39/102 (2006.01)

Patent

CA 1210695

-22- ABSTRACT OF THE DISCLOSURE A water-soluble covalent polysaccharide-exotoxoid conjugate having a molecular size between 140,000 and 4,500,000 dalton and a ribose/protein ratio between 0.25 and 1.00, capable of producing T-cell dependent antibody response to polysaccharide from H. influenzae b, is prepared by mixing a derivatized diphtheria or tetanus toxoid in a substantially cyanogen halide-free solution with a cyanogen halide-activated capsular H. influenzae b polysaccharide hapten consisting of approximately equimolar amounts of ribose, ribitol and phosphate, which polysaccharide had previously been heat sized until more than 60% attained a molecular size between 200,000 and 2,000,000 dalton.

431535

Affiliated with

Also associated with

Rating

Haemophilus influenzae b polysaccharide exotoxoid conjugate... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Haemophilus influenzae b polysaccharide exotoxoid conjugate..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Haemophilus influenzae b polysaccharide exotoxoid conjugate... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1319530