Haemophilus influenzae type b

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/74 (2006.01)

Patent

CA 2602665

Polypeptides comprising various amino acid sequences derived from Haemophilus influenzae type b, including a number of lipoproteins. These can be used in the development of vaccines for preventing and/or treating bacterial meningitis. They may also be useful for diagnostic purposes, and as targets for antibiotics. Antibodies against the polypeptides are also disclosed, as are the coding nucleic acids.

L'invention porte sur des polypeptides comprenant diverses séquences d'acides aminés dérivées de Haemophilus influenzae de type b, y compris un nombre de lipoprotéines. Celles-ci peuvent être utilisées dans le développement de vaccins pour prévenir et/ou traiter la méningite bactérienne. Elles peuvent être également utilisées à des fins de diagnostic et comme cibles pour des antibiotiques. L'invention porte également sur des anticorps contre les polypeptides et sur les acides nucléiques codants.

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