Haemopoietic growth factor antagonists and uses therefor

Details Haemopoietic growth factor antagonists and uses therefor Haemopoietic growth factor antagonists and uses therefor

C - Chemistry, Metallurgy

07

K

C07K 14/535 (2006.01) A61K 38/18 (2006.01) A61K 38/19 (2006.01) C07K 1/14 (2006.01) C12N 5/06 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2225517

The present invention relates generally to variant recombinant forms of haemopoietic growth factors useful as antagonists to the corresponding native haemopoietic growth factor and their use in ameliorating aberrant effects caused by the native molecules and in the treatment of tumours and cancers and inflammation.

L'invention concerne de manière générale des formes recombinées de facteurs de croissance hématopoïétiques, s'utilisant comme antagonistes dirigés contre le facteur de croissance hématopoïétique natif correspondant, et leur utilisation pour réduire les effets aberrants dus aux molécules natives et pour traiter des tumeurs, des cancers et l'inflammation.

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