Haemopoietic maturation factor

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/18 (2006.01) A61K 31/70 (2006.01) A61K 38/18 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) C07H 21/04 (2006.01) C07K 14/475 (2006.01) C07K 16/22 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2181431

Disclosed is a human maturation factor polypeptide and DNA(RNA) encoding such haemopoietic maturation factor polypeptides. Also provided is a procedure for producing such polypeptide by recombinant techniques and antibodies against such polypeptide. Such polypeptides may be combined with a suitable pharmaceutical carrier or diluent to provide diagnostic, therapeutic and/or prophylactic effects against various diseases related to the underexpression of such human haemopoietic maturation factor polypeptide.

On décrit un facteur de maturation hématopoïetique polypeptidique humain et l'ADN(ARN) codant pour de tels facteurs de maturation hématopoïetiques polypeptidiques. On décrit également un procédé pour produire ces polypeptides par des techniques de recombinaison et des anticorps dirigés contre ces polypeptides. Ces polypeptides peuvent être combinés avec un vecteur ou un diluant pharmaceutique approprié, pour diagnostiquer ou effectuer chez l'homme un traitement curatif et/ou préventif de diverses maladies liées à une expression insuffisante de ce facteur de maturation hématopoïetique polypeptidique.

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